The Clone Wars takes place between movies II and III, with characters from both films, so for many of the episodes, you knew that Anakin/Obi-Wan/Padme/any named Jedi were NEVER in danger since they survive to be in that next movie (Revenge of the Sith). The Trooper-centric episodes were the best ones, IMHO.
Rebels takes an all new cast of characters who interact with characters from the next movie, but we still don’t know the fate of these characters on the series, except for Hera and Chopper (as of Rogue One). They could all be gone by the time of Episode IV.
Your thoughts?